The following article describes in detail the motivation for creating the highdicom library, the design goals of the library, and experiments demonstrating the library’s capabilities. If you use highdicom in research, please cite this article.

Highdicom: A Python library for standardized encoding of image annotations and machine learning model outputs in pathology and radiology. C.P. Bridge, C. Gorman, S. Pieper, S.W. Doyle, J.K. Lennerz, J. Kalpathy-Cramer, D.A. Clunie, A.Y. Fedorov, and M.D. Herrmann.